DEVELOPMENT OF CORTICAL GABAERGIC INNERVATION

Development of Cortical GABAergic Innervation

The mature neocortex contains many different classes of GABAergic inhibitory interneurones, distributed, with some degree of selectivity, through six layers and through many different regions.Some of the events in the early lives of these neurones that may determine their ultimate destination, their maturation and their selective innervation of tar

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Integrative proteomics and tissue microarray profiling indicate the association between overexpressed serum proteins and non-small cell lung cancer.

Lung cancer is the leading cause of cancer deaths worldwide.Clinically, the treatment of non-small cell lung cancer (NSCLC) can be improved by the early detection and risk screening among population.To meet this need, here we describe the application of extensive peptide level fractionation coupled with label free quantitative proteomics for Vertex

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Imputing amino acid polymorphisms in human leukocyte antigens.

DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility to a wide range of human diseases.The complex genetic structure of the major histocompatibility complex (MHC) makes it difficult, however, to collect genotyping data in large cohorts.Long-range linkage disequilibrium between HLA loci and SNP markers across the

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